Former PhD student

Montserrat Llanses Martinez

I have always been interested in the role of tumour microenvironment in cancer. I am particularly fascinated by the significance of the remodelling of the extracellular matrix (ECM) as a key player in the development of malignant tumours, migration, invasion and subsequent metastasis. My research predominantly focused on characterising the endocytic pathways and regulators that control ECM internalisation in invasive breast cancer. In collaboration with Dr Frederic Bard (Institute of Molecular and Cell Biology, A*STAR, Singapore) I developed a high content screening to unravel regulators of this process. Moreover, I characterised how ECM endocytosis impinged on cancer cell proliferation, migration and invasion.

Former PhD student

Keqian Nan

My study aimed at understanding how ECM internalisation altered migratory behaviour of invasive breast cancer cells and characterise the roles of integrin receptors in this process.

Former PhD student

Shengnan Yuan

​My project is to investigate the role of ADAMTS5 as a protease in ovarian cancer metastasis, and how it is regulated.

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My PhD thesis is available here